CBD (cannabidiol) is a derivative from the HEMP plant, one of many Cannabis sativa plants. It carries many human health benefits and helps control or reduce significant side effects of many health conditions. THC also has CBD in it, but at low levels, while the HEMP plant contains high concentrations.
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What Does This Actually Mean and Why Is It Mentioned Here?
The answer is quite simple. CBD has been growing in popularity over the years and gaining new attention because of its non-high benefits and having little to no side effects. States are discovering the positive aspects of CBD and enacting new laws to open the door to new possibilities. While the DEA still technically labels CBD as illegal, there are stipulations permitting its use. People are discovering the benefits of CBD to treat major medical conditions, which can lead to healthier living and healthier lifestyles.
Numerous CBD experiments/studies in both small animals and humans have presented great results when used on a variety of health conditions, such as:
• Chronic anxiety
• Parkinson’s disease
• Schizophrenia
• Depression
• Cancer
• And more
More human studies are still needed to determine the true benefits of CBD use on a wide variety of health conditions, especially since only a limited number of clinical tests have been conducted. With the gaining popularity of positive health claims when using CBD, it is definitely getting more attention. While there have been numerous cell studies and animal testing, it does not provide enough evidence to report true benefits and disadvantages, but it is definitely getting closer to that mark.
So far, CBD has been reported to provide positive anti-seizure advantages in rats, as referenced with “J Pharmacol Exp Ther. 1977 Apr; 201 (1): 26-32.” Neurotoxic and anticonvulsant effects of cannabidiol (CBD) were compared to those without. CBD served as an effective anticonvulsant for audiogenic and maximal electroshock seizure tests. It was shown to reduce the anticonvulsant potencies of trimethadione, clonazepam, chlordiazepoxide, and ethosuximide. In addition, “Seizure. 2012 Jun;21(5):344-52” showed that Cannabidiol provided anti-convulsant effects in rodent models of both partial and temporal lobe seizures.
CBD Human Trials
Within the small amount of CBD human tests and trials that have been conducted over the years, positive outcomes have been generated from those trials and experiments.
CBD and Child Epilepsy
A parent survey was conducted on trials using cannabidiol-enriched cannabis in children with treatment-resistant epileptic conditions. The survey was given to parents that were part of a Facebook group. The group shared information about the results of treating their child’s seizures using cannabidiol-enriched cannabis. 13 had children with Dravet syndrome while 4 had Doose syndrome. In addition, 1 had idiopathic epilepsy and Lennox-Gastaut syndrome. For each report, a mathematical average of 12 other antiepileptic drugs was used before trying the CBD option. 84% of all 19 parents reported fewer seizures in their child while using CBD-enriched cannabis. 2 of the 19 parents reported that their child had no seizure activity, while 8 claimed an 80% reduction in seizure frequency.
Schizophrenia and CBD
CBD offers antipsychotic effects as found in tests with both animal models and human volunteers. “Curr Pharm Des. 2012;18(32):5131-40“ states that CBD has prevented human experimental psychosis and that it worked effectively in case reports and trials for patients with schizophrenia. It also states that functional magnetic resonance imaging (fMRI) suggests that CBD antipsychotic effects with psychotomimetic effects from delta9-Tetrahydrocannabinol include the involvement of the temporal cortex and the striatum, which are associated with psychosis.
CBD Trials on Parkinson’s Disease
Another disease known as Parkinson’s disease haunts many individuals across the globe and produces uncomfortable pain, altered motor skills, and more at a gradual pace over time. The body’s cannabinoid system plays a significant role in the slow-progressing effects of the disease. CBD is a cannabinoid in itself that does not alter existing bodily cannabinoids, it promotes the use of them.
According to “J Psychopharmacol. 2014 Nov;28(11):1088-98,” 21 Parkinson’s patients without comorbid psychiatric conditions and dementia were selected out of 119 patients to study the effects of CBD as a treatment for Parkinson’s disease. The results of the study leaned towards CBD improving quality of life measures with patients that do not have other conditions in addition to Parkinson’s disease.
In addition, “J Psychopharmacol. 2009 Nov;23(8):979-83” directly evaluated the safety, tolerability, and beneficial results of CBD on Parkinson’s patients with psychotic symptoms. All patients started with 150 mg/day for 4 weeks in conjunction with existing treatments. Both the Parkinson Psychosis Questionnaire and the Brief Psychiatric Rating Scale showed a significant decrease when CBD was used as a treatment. Unified Parkinson’s Disease Rating Scale scores were reduced and CBD did not worsen motor functionality. There were no adverse effects reported and all data promoted the potential of CBD to be safe, effective, highly tolerated for the treatment of psychosis in patients with Parkinson’s disease.
As represented by many CDB trials for a wide variety of health conditions, CBD does not appear to show any negative side effects and it promotes positive influences on the human body. It has basically shown thus far that it helps patients with various health conditions. It lets them manage life better and maintain more control over the symptoms generated by the disease at hand. The information above is just a sample of many trials and experiments that have provided beneficial results. In fact, it has been scientifically tested on many more life-debilitating issues than what has been discussed above.
